alexa Chemistry and Pharmacological Importance of 1,3,4-Oxadiazole Derivatives
e-ISSN: 2319-9849

Research & Reviews: Journal of Chemistry
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Research Article

Chemistry and Pharmacological Importance of 1,3,4-Oxadiazole Derivatives

Sharma R1*, Kumar N1 and Yaday R2

Department of Pharmacy, Oxford College of Pharmacy, UPSIDC, Ghaziabad, India

Department of Pharmacy, Banasthali Vidyapith, Rajasthan, India.

*Corresponding Author:
Sharma R
Department of Pharmacy
Oxford College of Pharmacy
UPSIDC, Masoorie-Gulawati road
Ghaziabad, India
Tel: +919837751352
E-mail: [email protected]; [email protected]

Received date: 06/04/2015 Accepted date: 23/04/2015 Published date: 27/04/2015

 

Abstract

Oxadiazole is an important heterocyclic compound containing one oxygen and two nitrogen atoms in the five membered ring. 1,3,4-oxadiazole is a versatile heterocyclic nucleus having novel molecule which attract the medicinal chemist to search a new therapeutic molecule. The present review summarizes physicochemical properties, various synthetic procedures and various pharmacological activities of 1,3,4-oxadiazole moiety. 1,3,4-oxadiazole moiety is an important pharmacophore which plays a major role in the pharmaceutical chemistry and broad range of important biological activities such as anti-inflammatory, analgesic, ulcerogenic, antimicrobial, antifungal antitubercular, anticonvulsant, anticancer/antitumor, antiviral, and antihypertensive activities etc. as reported in the literature.

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