alexa Comparison of L-Arginine and Hydroxyurea Interactractio
e-ISSN: 2319-9849

Research & Reviews: Journal of Chemistry
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Comparison of L-Arginine and Hydroxyurea Interactractions with Transitional Metal Ions.

Sangeeta Parab*, AV Chitre, and Harshada Gurav

Chemistry Department, Jai Hind College, Churchgate, Mumbai, India

*Corresponding Author:
Sangeeta Parab
Chemistry Department
Jai Hind College, Churchgate
Mumbai, India

Received: 10/03/2014 Accepted: 26/03/2014

 

Abstract

No* is a free radical with one free electron and as such it is very highly reactive and particularly it interacts with transitional metals. Nitric oxide, gas is an important signaling molecule in the body of mammals, including humans and is an extremely important intermediate in chemical industry In biological systems there are many enzymes, which contain transitional elements like iron, copper and manganese, which are the most probable sites for nitric oxide to react. Such type of interactions results in considerable modification of the enzyme functions resulting pathological and even genetic disorders. This needs a critical amount of nitric oxide in the system for proper functioning. To observe the effects of NO*, various NO* donor compounds are used. Hydroxyurea (HU) is shown to increase the levels of NO*.L-arginine is one of the non- essential amino acids. In the body L-arginine is used to make nitric oxide, which reduces blood vessel stiffness, increases blood flow and improves blood vessel function. The visible spectra of some transitional metals Cu, Fe(II),Fe(III),Cr, Mn, Ni have been studied individually in presence of hydroxyurea (HU) with varying amounts .The spectra are also studied for the effect of varying amounts of metal ion on hydroxyurea. To observe how arginine itself acts on transitional metal ions. Even effect of Hydroxyurea on metal-arginine binding is also studied. The evaluation of these spectra is carried out for its binding parameters with the help of scatchard plots. The work has revealed certain very significant and interesting data which can have a lot of bearing on many chemical, biological and environmental aspects.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords