alexa EFFECT OF CHROMIUM AND PROTEINS DIETS IN RATS


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Research Article

EFFECT OF CHROMIUM AND PROTEINS DIETS IN RATS

Amoikon Kouakou Ernest*, Kouame Koffi Gustave and Kati-Coulibaly Séraphin
Université de Cocody-Abidjan, UFR Biosciences Laboratoire de Nutrition et Pharmacologie, BP 582 Abidjan 22, Côte d’Ivoire
Corresponding Author: Amoikon Kouakou Ernest, Tel: (225) 07 61 21 44, E-mail: amoicom@yahoo.fr
Received: 03 February 2012 Accepted: 10 February 2012
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Abstract

A study was conducted to improve the effects of chromium tripicolinate (CTP) on the growth, organs weight and serum metabolites in rats fed on different proteins sources. Four groups of six growing male rats were fed on control diets containing casein, fish powder, soybean meal, cotton seeds meal. Four other groups of six growing male rats were fed on the control diets supplemented with 100 ppm of chromium as chromium tripicolinate (CTP). The diets were formulated to provide 14.76 % of crude proteins and 4417.6 kcal of brute energy per kg of dry matter. Results showed that chromium in association with proteins did not improve growth characteristics in rats. Cr+casein increased average weight of liver and kidneys, decreased (P≤0.05) average level of aspartate transaminase, alanine transaminase and total bilirubin. Both supplements increased average level of glucose and uric acid, and that of serum ions (Na+, Fe2+, Mg2+). Cr+fish powder decreased average spleen weight, average level of serum triglycerides, Na+ and Mg2+, and increased average level of serum uric acid. Cr+soybean meal reduced average level of serum urea, creatinine, and Fe2+. Cr+cotton seeds meal reduced average weight and serum level of total bilirubin. All these changes in average level of serum metabolites indicate that chromium and casein are more likely to affect liver functions. Moreover, fish, soybean and cotton seeds proteins affect level of very few metabolites.

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