alexa Fabrication of gelatin based composites containing bim
ISSN ONLINE(2319-8753)PRINT(2347-6710)

International Journal of Innovative Research in Science, Engineering and Technology
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Research Article

Fabrication of gelatin based composites containing bimetallic Ag-Au nanoparticles for biomedical applications

A. Mandal1 and T.P. Sastry2*
  1. ResearchStudent, Centre for Nano-Biotechnology, School of Bio-Sciences and Technology, VIT University, Vellore 632014, India
  2. Senior Principal Scientist & Head, Bioproducts Lab, CSIR-Central Leather Research Institute, Adyar, Chennai 600020, Tamil Nadu, India
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Recently, focus is directed on research which involves synthesis of nanoparticles using natural polymericmaterials that are eco friendly, inexpensive as well as biodegradable. In this study, bimetallic silver-gold nanoparticles (Ag-AuNPs) were synthesized usinggelatinextracted from chrome containing leather waste as a template.The nanoparticles were confirmed with UV-Vis and particle size analysis. The gelatin directed bimetallic nanoparticles were air driedto obtain as nanobiocomposites (NBCs). These NBCs were characterized via FTIR, DSC, TGA, XRDand SEM/EDX. Also, mechanical properties such as tensile strength and Young’s modulus along with water absorption studies of the NBCs were conducted.The results indicate that the gelatin NBCs incorporated with bimetallicnanoparticles are biodegradable and possess the desired mechanical propertiesneededfor biomedical applications. Moreover, the in vitro results demonstrate the viability of fibroblast (NIH 3T3) cells with gelatin based NBCs.The gelatin NBCincorporated with Ag-Au NPs isbiocompatible and can be used as scaffolds which have potential for various biomedical applications.


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