alexa Natural Bone Regeneration with L-PRF and Healing Advantages after Enucleation of Large Radicular Cyst in Lower Jaw: Case Report
e-ISSN: 2320-7949 and p-ISSN: 2322-0090

Research & Reviews: Journal of Dental Sciences
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Case Report

Natural Bone Regeneration with L-PRF and Healing Advantages after Enucleation of Large Radicular Cyst in Lower Jaw: Case Report

Dr. Andrea Vinci1*, Re M2, Conte G3, Pitruzzella C3, Seidita F4, Romano S4, Tela V4, Mignano F4, Tarallo V4,Crescentini F3 and Cipollina A5

1Istiuto Clinico Locorotondo, Palermo, Italy

2Freelance professional, Messina, Italy

3Locorotondo Clinical Institute (PA), Italy

4Freelance professional, Palermo, Italy

5Director of oral surgery, Locorotondo Clinical Institute (PA), Italy

*Corresponding Author:
Dr. Andrea Vinci
Istiuto Clinico Locorotondo
Via Gaetano Daita
15 - 90139 Palermo, Italy
Ph: +39 340 2509130
E-mail: [email protected]

Received Date: 12/04/2016; Accepted Date:06/06/2016; Published Date: 13/06/2016




Objectives: The aim of the study is to show how cysts of larger dimensions can be treated, achieving early recovery with good predictability results, a low surgical impact on the patient and a follow-up of modest clinical relevance through high-level technological procedures in which the fibrin scaffold represented by L-PRF (Leukocyte–Platelet Rich Fibrin) is the biological signature that promotes the rapid healing.

Material and Methods: Microsurgery procedures were used for bone regeneration in a large cystic lesion. The cystic lesion was initially treated with LASER LBO 532 nm with the aim of obtaining debridement of the cystic lumen. Subsequently the osteolytic lesion was filled with L-PRF (Leukocyte and Platelet Rich Fibrin) membranes; L-PRF is one of the 4 main families of platelet concentrates for surgical use, and it is frequently used in oral and maxillofacial surgery as a surgical adjuvant to improve healing and promote tissue regeneration. In order to direct and stimulate bone regeneration further, the patient underwent postoperative sessions with Combined Magnetic Fields (CMFs).

Results: Using this surgical procedure, immediate positioning of the implants was possible on regenerated bone after only 4 months. Histological exams were made harvesting bone samples during implants placement.

Conclusion: L-PRF was used for the regeneration of large mandibular cysts, taking advantage of the regenerative abilities of blood in addition to those of physical medicine. This resulted in a notable time reduction in the regeneration of vast bone lesions.


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