ISSN ONLINE(2319-8753)PRINT(2347-6710)

International Journal of Innovative Research in Science, Engineering and Technology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article


Darshan N1, Sneha B Shetty2 *, Nayanatara AK2, Sheila R Pai2,Balachandra.A.Shetty1
Department of Medicine, A.J. Institute of Medical Sciences, Mangalore, Karnataka, India1
Departments of Physiology, Center for Basic Sciences, Kasturba Medical College (Manipal University) Bejai,Mangalore-575004, Karnataka, India2
Related article at Pubmed, Scholar Google


The present study was aimed to evaluate the dispersion of QT interval, which is an index of inhomogeneity of ventricular repolarization and heart rate, and a measure of cardiac autonomic modulation in patients with clinical hypothyroidism .A total of 60 comprising of 30 healthy subjects who underwent TSH estimation for any other reasons and found to be normal were taken as control group and 30 patients who are diagnosed with clinical hypothyroidism, were selected from outpatient clinic of Department of General Medicine were taken as cases.. The ECG was recorded with BPL Cardiart 6108 T ECG Machine (BPL Manufacturing Company, BPL limited, India) and heart rate and QT dispersion was calculated. The mean QT intervals in all the leads of ECG differed significantly (p<0.05) between hypothyroid cases and normal control cases except in lead I . Mean QTc from the cases differed significantly (p<0.5) from the control group . Both QTmin and QTmax of cases and controls showed statistical significant difference (p=0.22 and P=0.014 respectively). Hypothyroid patients showed a highly significant increase(p<0.0001) in mean QTdis in respect to control group. In conclusion, the present study confirms the role of thyroid hormones on the cardiovascular functionality, especially on the ventricular repolarization and autonomic modulation of cardiac activity.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version