Retinoids and Reproduction
- *Corresponding Author:
- Sandip Ghosh,Department of Biochemistry,KPC Medical College ,1 F,raja S. C. Mullick Road,Jadavpur,West Bengal,India.
Received date: 27 March 2013 Accepted date: 10 May 2013
Retinoids are essential for reproduction. Rats maintained on a diet deficient in retinol but containing instead retinoic acid grow well and outwardly healthy. But they lose the vision and ability to reproduce. The rats with vitamin A deficiency have lowered testosterone levels which can be restored by retinoic acid. Again retinoic acid cannot restore germinal epithelium of the seminiferous tubules in Vitamin A deficient rats. The action of retinoic acid is required for the commitment of germ cells to enter meiosis in both mammalian males and females