alexa Retinoids and Reproduction
ISSN: 2319-9865

Research & Reviews: Journal of Medical and Health Sciences
Open Access

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Review Article

Retinoids and Reproduction

Salil Kumar Mandal1,Sandip Ghosh2*,and Chittaranjan Maity3.

Professor & Head ,Department of Physiology,KPC Medical College,Jadavpur,West Bengal,India.

Assistant Professor,Department of Biochemistry,KPC Medical College,Jadavpur,West Bengal,India.

Professor & Head ,Department of Biochemistry,KPC Medical College,Jadavpur,West Bengal,India.

*Corresponding Author:
Sandip Ghosh,Department of Biochemistry,KPC Medical College ,1 F,raja S. C. Mullick Road,Jadavpur,West Bengal,India.

Received date: 27 March 2013 Accepted date: 10 May 2013

 

 

 

Abstract

Retinoids are essential for reproduction. Rats maintained on a diet deficient in retinol but containing instead retinoic acid grow well and outwardly healthy. But they lose the vision and ability to reproduce. The rats with vitamin A deficiency have lowered testosterone levels which can be restored by retinoic acid. Again retinoic acid cannot restore germinal epithelium of the seminiferous tubules in Vitamin A deficient rats. The action of retinoic acid is required for the commitment of germ cells to enter meiosis in both mammalian males and females

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