alexa Role of Solvents and Stabilizer in the Preparation of S
ISSN ONLINE(2319-8753)PRINT(2347-6710)

International Journal of Innovative Research in Science, Engineering and Technology
Open Access

Like us on: https://twitter.com/ijirset_r
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Special Issue Article

Role of Solvents and Stabilizer in the Preparation of Solid Lipid Nanoparticles of Stearic Acid by Ultrasound Assisted Nanoprecipitation Method

 
To read the full article Peer-reviewed Article PDF image

Abstract

This article describes the preparation and characterization of solid lipid nanoparticles (SLN) of stearic acid with two different stabilizer systems and mixture of solvents in order to study the influence of solvents and surfactants on the size of the nanoparticles, degree of dispersion, stability and crystallinity of the SLN. A 1:1 mixture of TWEEN-80 and SDS and another stabilizer system containing 1:1 mixture of CTAB and PVP were used as stabilizes. Acetone, mixture of acetone and THF and ethanol were used as solvents. The SLN were characterized by time-resolved particle size analysis, zeta potential measurements, differential scanning calorimetry (DSC) X-ray diffraction (XRD), Transmission electron microscopy(TEM) and FTIR. Results indicate that the SLN produced with the stabilizer system of TWEEN-80 and SDS have lower crystallinity, larger particle sizes, lower melting point as compared with SLN prepared with PVP and CTAB. However the polydispersity indexes for the suspensions are lower than the SLN prepared with PVP and CTAB indicating higher stability. FTIR spectra reveals that there is no structural change occur in all the SLN

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords