alexa Synthesis, Spectroscopic Characterization and Antibacte
e-ISSN: 2320-0812 p-ISSN: 2347-2340

Research & Reviews: Journal of Pharmaceutical Analysis
Open Access

Like us on: https://twitter.com/pharm_analysis
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Synthesis, Spectroscopic Characterization and Antibacterial Properties of some Metal (II) Complexes of 2-(6-methoxybenzothiazol-2- ylimino)methyl)-4-nitrophenol.

Aderoju A Osowole*, Anthony C Ekennia, and Benedict O Achugbu

Inorganic Chemistry Unit, Department of Chemistry, University of Ibadan, Ibadan, Nigeria.

Corresponding Author:
Aderoju A Osowole
Inorganic Chemistry Unit,
Department of Chemistry,
University of Ibadan, Ibadan,
Nigeria.

Received Date: 03/02/2013; Accepted Date: 09/04/2013; Published Date: 13/04/2013

 

Abstract

Mn(II), Co(II), Ni(II), Cu(II), Zn(II), and Pd(II) complexes of the Schiff base 2-(6-methoxybenzothiazol-2-ylimino)methyl)-4-nitrophenol (HL) derived from condensation of 2-hydroxy-5-nitrobenzaldehyde and 2-amino-6-methoxybenzothiazole have been synthesized and characterized by percentage metal, solubility, infrared and electronic spectra measurements. Their in-vitro anti-bacterial activities against Bacillus subtilis, Staphylococcus aureus, Proteus mirabilis, Klebsiella oxytoca, Pseudomonas aeruginosa, and Escherichia coli were also evaluated. The metal complexes formed as [ML(NO3)].bH2O, where M = Mn, Co, Cu, Zn; b = 0.5 - 4, with the exceptions of the Pd(II) and Ni(II) complexes that analyzed as [Pd(L)2 ].4H2O and [Ni(L)Cl(H2O) ]. The infrared spectra confirmed that coordination by the Schiff base is via the imine nitrogen and phenol oxygen atoms respectively, resulting in a NO chromophores around the metal ion. The electronic spectra measurement was corroborative of a 4-coordinate tetrahedral/square planar geometry for the complexes. The complexes mostly exhibit good in-vitro antibacterial activities against S. aureus, E. coli and P. mirablilis with inhibitory zones range of 16.0-27.0 mm, 13.0-15.0 mm and 17.0-20.0 mm respectively. Its noteworthy that the Pd(II) and Zn(II) complexes had broad spectrum anti-bacteria activity against the bacteria used with the exception of B. subtilis with inhibitory zones range of 13.0-22.0 and 13.0-27.0 mm respectively.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords