|Pharmaceutical analysis may be defined as a procedure or the sequences of progressions to identify or quantify a constituent or drug, the mechanisms of a pharmaceutical solution or fusion or the determination of the structures of chemical combinations used in the formulation of pharmaceutical product.
Celiac disease (CD) is a gluten-sensitive, immuneâmediated
chronic enteropathy with a wide range of manifestations of variable
severity. This disease is due to the damage of intestinal mucosa as a
result of the action of gluten, in genetic predisposed people. The masks
that can diagnose celiac disease, presented below, are divided into:
classical Celiac disease, non-classical Celiac disease, subclinical Celiac disease and potential Celiac disease. The
clinical manifestations and histology changes of small bowel mucosa
will disappear with gluten-free diet, but histological relapses will
appear in a variable period of time after re-use of foods with gluten.
Prevalence of this disorder is difficult to estimate due to the variability
of clinical presentation. Lifelong avoidance of gluten ingestion is the
main treatment for patients with celiac disease. It is characterized by gastrointestinal signs and symptoms. Typical
form of the disease begins at various times after foods that contain
gluten are introduced into the diet. Characteristic manifestations of
infants and young children are chronic diarrhea, vomiting, anorexia,
abdominal distention, abdominal pain, and poor weight gain or
weight loss. Nutritional deficiency syndrome occurs in time and its
manifestations are: growth deficiency, psychomotor development
deficiency, anemia, rickets, and hemorrhagic manifestations.
Undiagnosed and severely affected infants may present celiac crisis
characterized by explosive diarrhea, marked abdominal distention,
dehydration and lethargy. Delayed diagnosis and persistent symptoms
can cause severe malnutrition