Photodynamic theraphy (PDT) is a type of phototheraphy which uses nontoxic photosensitive compounds that are exposed by selection to light, where as they become toxicant to targeted malignant and different diseased cells. PDT has the ability to kill microbic cells, together with microorganism, fungi and viruses. PDT is popularly employed in treating disease of the skin. It is used clinically to treat medical conditions, together with wet age-related devolution and malignant cancers, and is recognised as a treatment strategy that is each minimally invasive and minimally toxicant.
Most modern PDT applications involve 3 key components namely a photosensitizer, a light-weight supply and tissue element. The mixture of those 3 parts results in the chemical destruction of any tissues that have either by selection preoccupied the photosensitizer or regionally exposed to light. The wavelength of the sunshine supply has to be applicable for exciting the photosensitizer to supply reactive element species. These reactive element species generated through PDT are free radicals (Type I PDT) generated through negatron abstraction or transfer from a substrate molecule and extremely reactive state of element called undershirt element (Type II PDT). In understanding the mechanism of PDT it's necessary to differentiate it from different light-based and optical device therapies like optical device wound healing and rejuvenation, or intense periodical light-weight hair removal, that don't need a photosensitizer.
Last date updated on September, 2014