|Bone homeostasis is maintained through a delicate balance between osteoblastic bone formation and osteoclastic bone resorption. Numerous pathological processes have the capacity to disrupt this equilibrium leading to conditions where the rate of bone resorption outpaces the rate of bone formation leading to osteoporosis, a devastating bone disease that is widely recognized as a major public health threat. Bone loss is accelerated with increasing age, inducing elderly osteoporosis. Postmenopausal osteoporosis, a consequence of ovarian hormone deficiency, is the archetypal osteoporotic condition in women after menopause and leads to bone destruction though complex and diverse metabolic and biochemical changes. Moreover, osteoporosis is induced through obesity, diabetes, and inflammation and cancer cell bone metastasis. The most dramatic expression of this disease is represented by bone fractures.
Osteoporosis Treatment with Functional Food Factor: Vitamin K2: Masayoshi Yamaguchi