Exercise is an important component in disease prevention, treatment and rehabilitation. Certain physiological changes caused by exercise may alter the absorption, distribution, metabolism and elimination (pharmacokinetic parameters) of some medications used to treat common medical conditions. Alternatively, certain medications can limit exercise capacity. In both cases, scientific literature exists to show that that an interaction exists between exercise and certain medications. Drug-exercise pharmacokinetic interactions alter the performance of medications especially under conditions where exercise is performed for a long period of time. Particular medications that may be effected are those with a narrow therapeutic dosing range, such as digoxin, theophylline, and warfarin. Other medications including insulin and those administered via transdermal patch drug delivery system may have an adverse effect during shorter bouts of exercise.
Drug-exercise interactions: Thomas L. Lenz
Last date updated on June, 2014