"Preeclampsia, affecting 2-7% of all pregnancies, is a vasculopathy that results from aberrant placenta development and it is the third highest cause of pregnancy related deaths following hemorrhage and embolism. While the etiology of preeclampsia is poorly understood, a leading theory is that insufficient spiral artery remodeling in the placenta may result in a hypoxic environment with reperfusion injury and up-regulation of oxidative stress. The preeclamptic lacenta secretes factors such as inflammatory cytokines and reactive oxygen species into maternal circulation to induce hypertension through local production of vasoconstrictors, notably endothelin-1. As a result, the mother shows signs of preeclampsia after the 20th week of gestation by new onset hypertension and proteinuria.
OMICS Group International is one of the leading Open Access Publishers which is publishing 700+ peer-reviewed journals with the support of 50,000+ editorial board members as editorial team and aimed to disseminate the scholarly knowledge to the scientific society. OMICS Group also organizing 3000+ International Scientific Conferences and events yearly all over the world with the support of 1000+ Scientific associations worldwide.
Citation: Wong F, Cox B (2014) Proteomics Analysis of Preeclampsia, a systematic Review of Maternal and Fetal Compartments. J Proteomics BioinformS10: 001."
Last date updated on July, 2014