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Prion Diseases

"In 2013, there are other researches on rabbits for diseased prions (PrPSc). Wang et al. (2013) aimed to investigate “potential mechanisms contributing to prion resistance or susceptibility by using the rabbit, a species unsusceptible to prion infection, as a model and investigated “the expression level and distribution of LRP/LR (laminin receptor precursor or laminin receptor) in rabbit tissues by real-time polymerase chain reaction and by immunochemical analysis with a monoclonal anti-67 kDa LR antibody “and at last their findings confirmed the prion resistance in rabbits. Sweeting et al. (2013) produced X-ray structures of mutants in the β2-α2 loop and reported that the helixcapping motif in the β2-α2 loop modulates β-state misfolding in RaPrP, and still acknowledged “rabbit PrP, a resistant species”. (Recent Advances in the Immunity Research of Rabbits to Prion Diseases : Jiapu Zhang) OMICS International with its open access journals represents the research findings and advancements in various scientific and medical disciplines. OMICS International provides access to 700+ peer-reviewed journals with no restrictions and thus promotes the Open Access movement with a view to promote scientific advancements. The research articles published in OMICS Group journals are immediately and permanently available online without charge. "
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Last date updated on July, 2025

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