|"Systematically addressing these fundamental questions since the premier publication of the Proteomic-Code hypotheses in 1981 to explain the nature and origin of specific protein-protein interactions. The first model suggested the perfect complementary coding of interacting (co-locating) amino acids in the specifically interacting peptides. It was thoroughly tested in several laboratories with promising but not conclusive results. The refined concept of Proteomic Code, that suggested partial complementary coding of co-locating amino-acids, was released in 2006. It was followed by the recognition of the significance of Proteomic Code to determine/ assist intra-molecular, residue-to-residue interactions, that is, the 3D structure of proteins.
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Citation: Biro JC (2014) Suggestion to Upgrade the Canonical Concept of Translation. J Proteomics Bioinform 7: 112-120."