Asthma is a chronic inflammatory disorder of the airways associated with airway hyperresponsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness and coughing. These episodes are usually associated with widespread, but variable, airflow obstruction within the lung. Chronic airflow obstruction is also characteristic of COPD but, in contrast to asthma, is not fully reversible, even under the action of bronchodilators, and is usually progressive. A combination of small airway disease -obstructive bronchiolitis - and parenchymal destruction - emphysema, leads to COPD clinical manifestation. A number of factors influence a personâs risk of developing these lung diseases, which include host factors, primarily genetic, and environmental factors, such as allergens and tobacco smoke in asthma and COPD, respectively.
Proteomics in Detection and Monitoring Chronic Lung Diseases: The Human Nasal Epithelium as a Molecular Model: TÃ¢nia SimÃµes, Nuno Charro, Bruno M. Alexandre and Deborah Penque LaboratÃ³rio de ProteÃ³mica, Departamento de GenÃ©tica, Instituto Nacional de SaÃºde Dr. Ricardo Jorge, Lisboa, Portugal
Journal of Pulmonary & Respiratory Medicine welcome articles related to "Airway disease"
Last date updated on July, 2014