|Impulse Oscillometry (IOS) is a noninvasive and validated technique that measures respiratory resistance and reactance at different oscillation frequencies. It was introduced as an alternative modality to the conventional pulmonary function test. IOS is effort independent. The pressure-flow oscillations are applied at the mouth superimposed on the subjectâs tidal breaths to measure respiratory system resistance and reactance. IOS has been used to measure post-bronchodilator (Pb) changes in asthmatic airways. Respiratory resistance at lower frequencies, particularly at 5 Hz (R5rs) has been shown to correlate with FEV1. Several works have been published showing that IOS can be used in adults as well as in preschool children to diagnose and evaluate pulmonary disease such as asthma and cystic fibrosis.
A Comparison of Impulse Oscillometry to Spirometry in the Evaluation of Exercise Induced Bronchoconstriction in Children with Asthma: Sebnem Ozdogan, Danny Hsia, Isabelo Elisan, Cheryl Johnson, Karen Hardy
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