Regucalcin

Regucalcin, which was discovered in 1978, plays a multifunctional role as a suppressor protein in signal transduction in various cell types and plays a cell physiologic role in maintaining cell homeostasis for various stimuli. Cytoplasmic regucalcin localizes into the nucleus, and it suppresses nuclear protein kinase and protein phosphatase activities and DNA and RNA synthesis and regulates gene expression for various proteins. Regucalcin has also been shown to suppress protein synthesis and activate proteolysis, suggesting a role as suppressor in protein turnover. Moreover, overexpression of endogenous regucalcin has been demonstrated to suppress cell proliferation and apoptosis induced through multisignaling pathways in various cell types. Thus, regucalcin plays a pivotal role in cell regulation. New Aspects in Obesity and Diabetes: Involvement in Regucalcin, a Suppressor Protein of Cell Signaling- Masayoshi Yamaguchi OMICS Group International is one of the leading Open Access Publishers which is publishing 700+ peer-reviewed journals. Cell & Developmental Biology is one of the best online open access journals which publish original research, review, Short communication, Case study in the field of cell biology. It has world quality editorial board members in order to develop its standards.

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Last date updated on April, 2024