Sex Chromosome Abnormalities (SCAs) are the most common genetic disorder with a frequency of 1/400 or 1/500 live births. Reproductive decisions based on genetic counseling of SCAs are complicated. Prenatally diagnosed diseases with uncertain consequences or moderate severity is the main subject of this complex decision making process. What is the most recent scientific approach in the elective termination of SCAs? Reproductive decisions post genetic counseling, in all genetic conditions; represent a dynamic interaction between patients, obstetricians and genetic counselors. A limited number of principles, guidelines and standards must be applied when counseling in regard to âtesting for fetal genetic disease.â These principles dictate that genetic counseling should be non-directive and unbiased and that parental decisions should be supported regardless of the reproductive choice. Consequently, an elective termination decision, following prenatally diagnosed SCAs and genetic counseling, is still a hotly debated topic which requires tight and insightful collaboration from all parties concerned as well as updated and relevant genetic information. Elective Termination Decision in Sex Chromosomal Abnormalities-Current Situation in Decision Making Process, Haluk Akin.
Last date updated on June, 2014