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Research Article Open Access
Back ground selection of empire antibiotics for urinary tract infections (UTI) has become more challenging because of the increasing rates of multi drug resistant infectious cultures. This respective study objective was to determine antibiotic resistance patterns, risk factors and appropriate empiric antibiotic selection for multi-drug resistant Urinary tract infectious cultures. Urinary tract infections are common among the female populations. Adult patients seen in emergency department with gram negative and gram positive infections , which are resistant to at least 5 different categories of antibiotics. This study concluded the antimicrobial activity of antibiotics against 6 different infectious and normal urine samples. The female sample shows more resistance towards antibiotics than the male samples. Among them the samples of diabetic patients show more resistance towards combined and mono therapy. In case of mono therapy Nitrofurantoin show more growth inhibition zone than Norfloxacin. As the concentration of drug increases the variation in growth inhibition is not varied much. We found 25% drug resistance against normal and 85% against abnormal samples due to different risk factors such as mutations, drug resistant plasmids and different physical pressures etc. So we concluded that the UTI therapy must be changed to protect the patients from fatal conditions.
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Author(s): Supriya CH., Nagakishore CH., P. Bhanuja, E. Swarnalatha, T. Bhargav Chaitanya
Antibiotics, drug resistance, gram positive, gram negative, infectious cultures, urine samples, Infectious Colitis