alexa Abstract | A Review on Research Methodologies of Diabetic Retinopathy

Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article Open Access


Cataract, opacity of the eye lens is a major complication of chronic diabetes leads to loss of vision and is the leading cause of blindness worldwide. Nearly 19 million people are blind due to cataract in the world. It is a result of increased polyol pathway activity, activation of protein kinase C (PKC), increased oxidative stress, and accumulation of advanced glycation end products (AGEs) due to prolonged hyperglycemia. In vitro and In vivo studies have suggested that the damage to lens is a result of oxidation and generation of free radicals. The antioxidants enzymes might protect the lens against the formation of cataract. Several invasive and non-invasive research methodologies have been in proceeding for the study of diabetic retinopathy. The research methodologies for retinal examinations that improve the cost-effectiveness and noninvasive, allows repeated assessment, and can be performed in a relatively short period of diabetic retinopathy were discussed in this review. Several image processing based methods have been developed in the last decade providing an alternative to first phase examinations by using slitlamp examination and fundoscopy of lens. Estimation of antioxidant enzymes like superoxide dismutase, catalase, aldose reductase, reduced glutathione and glutathione peroxidase and protein products such as malonaldehyde, sorbitol, α-crystalline, protein carbonyl content and estimation of advanced glycation end products and several inflammatory mediators by various approaches were discussed in the present review.

To read the full article Peer-reviewed Article PDF image

Author(s): Swathi Putta, Eswar Kumar Kilari


Diabetes mellitus, cataract, retinopathy, Etiology of Meningitis,Diabetic Amyotrophy,Diabetes Research and Clinical Practice,Diabetes Research and Clinical Practice,Diabetic Retinopathy

Recommended Journals

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version