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Review Article Open Access
Urolithiasis is one of the serious renal disorders that require a well targeted therapeutic strategy. A number of drugs including diuretics and stone inhibitors are available for the treatment of lithiaisis, but clinical evaluation of these drugs has shown incidence of relapses, side effects, and drug interactions. This has been the rationale for the development of new antilitiatic drugs and the search for novel molecules has been extended to herbal drugs that offer better protection and decreased relapse. Drugs of plant origin are gaining popularity and are being investigated for a number of disorders, including lithiasis. The present article reviews the antilithiatic activity of Melia Azedarach Linn., Aerva lanata and Vediuppu chunnam in combination, Petroselinum sativum, Lagenaria siceraria, Hygrophila spinosa, Glochidion velutinium, Tinospora sinensis, Relith, Musa paradisica, Fenugreek, Tecoma stans, Celosia argentea, Plectranthus tomentora Hordeum vulgare Linn., Moringa oleifera Lam., Achyranthes aspera, Asparagus racemosus, Rubia cordifolia, Cucumis trigonus and Mimusops elengi. The safest medicines than the allopathic medicines are Herbal system and here an attempt is made to review a some of phytoconstituents which is a potent antiurolithiatic and some medicinal herbs on which antiurolithiatic activity has been provedSome of the important plants reported for their antilithiatic activity have been highlighted in this study. Ayurvedic knowledge supported by modern science is necessary to isolate, characterise, and standardize the active constituents from herbal sources for antilithiatic activity.
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Author(s): Tushar Shelke, Sandesh Wayal, Shiv Gunjegaokar, Sachin Gaikwad, Amol Shirsath, Sunil Hadke