alexa Abstract | Anti-Inflammatory Activity of Methanol Extract of the Whole Plant of Psychotria octosulcata. W. A. Talbot

Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


In the present study, the anti-inflammatory effect of the methanol extract of the whole plant of Psychotria octosulcata was investigated. The methanolic extract of Psychotria octosulcata was ingested orally (p.o.) in the form of suspension in 0.5% Tween 80 in three different doses, (100,200 and 400 mg/kg body weight). The acute anti-inflammatory effect of Psychotria octosulcata was tested in carrageenan-induced paw oedema and chronic anti-inflammatory effect of Psychotria octosulcata was tested in cotton pellet granuloma pouch method in wistar albino rats and compared with the standard, diclofenac (40 mg/kg body weight). The results showed that Psychotria octosulcata has significant reduction (p≤0.01) in inflammation i.e. 67.94% (200 mg/kg body weight) in paw edema method and 72.61% (200 mg/kg body weight) in cotton pellet method as compared to the standard drug, diclofenac which was 69.23% and 74.85 respectively. These results indicate that the extracts could possess anti-inflammatory property. Both of the methods and the changes in the activities could be suggested as contributory effects to the use of Psychotria octosulcata in the management of inflammatory conditions.

To read the full article Peer-reviewed Article PDF image

Author(s): R. Mariyammal, S. Kavimani

Recommended Journals

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version