alexa Abstract | Antioxidant and Free Radical Scavenging Activities of Zingiberofficinale
ISSN ONLINE(2319-8753)PRINT(2347-6710)

International Journal of Innovative Research in Science, Engineering and Technology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


The present study was carried out to evaluate the antioxidant and free radical scavenging activity of ethanolic extract of ZingiberofficinaleRhizomes (Zingiberaceae) in various systems. DPPH radical, superoxide anion radical, nitric oxide radical and hydroxyl radicalscavenging assays were carried out to evaluate the antioxidant potential of the extract. The antioxidant activity of ethanolic extract increased in a dose dependent manner. About 50,100, 250 and 500 μg of ethanol extract of Zingiberofficinale(EZO) showed 61.44,66.25, 72.01 and 76.85% inhibition respectively on peroxidation of linoleic acid emulsion. Like antioxidant activity, the effect of EZO on reducing power increases in a dose dependentmanner. In DPPH radical scavenging assay the IC50 value of the extract was found to be 168.09μg/ml. EZO was found to inhibit the nitric oxide radicals generated from sodiumnitroprusside. The IC50 value was found to be 83.365 μg/ml, whereas the IC50 value of curcumin was 20.34 μg/ml. Moreover, the EZO was found to scavenge the superoxide generated byPMS/NADH-NBT system. EZO was also found to inhibit the hydroxyl radical generated byFenton's reaction, where the IC50 value of EZO was found to be more than 1000 μg/ml and for catechin the IC50 value was found to be 5 μg/ml, which indicates the prooxidant activity of EZO. The amounts of total phenolic compounds were also determined in this study. Theresults obtained in the present study indicate that the EZO can be a potential source of naturalantioxidant.

To read the full article Peer-reviewed Article PDF image

Author(s): M. Ismail Shareef, S.M. Gopinath, P. Jagan Mohan Reddy, K. S. Dayananda, Ajay Mandal, Purushotham K.M

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version