alexa Abstract | Assessment of Potential Antioxidant Activity of Polyphenolic Fraction Separated from Acalypha Indica Leaves: An In vitro Approach


Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

The free radicals are generated in normal cellular metabolic events .However they may be produced more in disease conditions when they directly interact with the bio molecules are dangerous to the normal life because they alter genetic material. Free radicals induce permanent modifications in genetic material that may lead to mutagenesis, carcinogenesis and aging. The prevention or treatment of diseases has direct link with antioxidants which can reduce the effect of free radicals. The phenolic compounds are functionally potent antioxidants and they have the ability to scavenge reactive oxygen species (ROS)/ reactive nitrogen species(RNS), suppress the ROS/RNS formation by inhibiting relevant enzymes, chelates trace metal elements responsible for free radical generation and up regulates or protects the antioxidant defense system. In this study, we attempted for the separation of Polyphenolic fraction from Acalypha indica leaves and tested for its antioxidant activity employing DPPH, H2O2 assays and also to assess its reducing power, total antioxidant power. The outcome of the results from this study showed that Polyphenolic fraction from the Acalypha indica leaves scavenges the in vitro free radicals to their stable forms such as DPPH radical to DPPH, Mo (VI) to Mo (V), ferric cyanide complex to ferrous form and hydrogen peroxide to water. The polyphenolic fraction has the reduction power against free radicals which suggests further studies to take up in in vivo for the treatment of various diseases due to free radicals generation.

To read the full article Peer-reviewed Article PDF image

Author(s): Sahukari Ravi, Bhasha Shanmugam, Singamala Hari Prasad, Ganjikunta Venkata Subbaiah, Kesireddy Sathyavelu Reddy

Recommended Journals

Share This Page

Additional Info

Loading
Loading Please wait..
 
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords