alexa Abstract | Aurora Kinase Inhibitors in Target Specific Cancer Treatment
e-ISSN:2320-1215 p-ISSN: 2322-0112

Research & Reviews in Pharmacy and Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Commentary Open Access


Targeted therapy is one of the major treatment modalities in medical oncology. Targeted therapy aims to inhibit oncogenic pathways by interfering with target biomolecules. For this reason drug designers have focused on investigation of new targets in order to develop efficient cancer drugs [1]. Aurora kinases are important members of the serine/threonine kinases and three forms of the Aurora kinases have been identified: Aurora-A, Aurora-B, and Aurora-C in human. Especially, Aurora-A and Aurora-B play key roles in mitotic checkpoint activation, chromosome orientation, cell proliferation, cytokinesis, and mitotic spindle formation in cells. Alteration of their expression level is related with mitotic errors and aberrant expression of these enzymes may trigger multiple oncogenic pathways. Therefore, Aurora-A and Aurora-B kinases have been potential targets in new generation cancer drug development research.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Yusuf Tutar


Aurora Kinase, Cancer drugs, Clinical phase studies., Aurora Kinase, Cancer drugs, Clinical phase studies

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version