alexa Abstract | Chemistry and Pharmacological Importance of 1,3,4-Oxadiazole Derivatives
e-ISSN: 2319-9849

Research & Reviews: Journal of Chemistry
Open Access

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Research Article Open Access

Abstract

Oxadiazole is an important heterocyclic compound containing one oxygen and two nitrogen atoms in the five membered ring. 1,3,4-oxadiazole is a versatile heterocyclic nucleus having novel molecule which attract the medicinal chemist to search a new therapeutic molecule. The present review summarizes physicochemical properties, various synthetic procedures and various pharmacological activities of 1,3,4-oxadiazole moiety. 1,3,4-oxadiazole moiety is an important pharmacophore which plays a major role in the pharmaceutical chemistry and broad range of important biological activities such as anti-inflammatory, analgesic, ulcerogenic, antimicrobial, antifungal antitubercular, anticonvulsant, anticancer/antitumor, antiviral, and antihypertensive activities etc. as reported in the literature.

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Author(s): Sharma R,  Kumar N,  Yaday R

Keywords

Oxadiazole, Anti-inflammatory, Analgesic, Antitubercular, Anticonvulsant, Anticancer/Antitumor and Antiviral activities, Forensic Environmental Chemistry,Pharmaceutical Chemistry,Nano Chemistry

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