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Research Article Open Access
Natural resources have since antiquity been extensively exploited for medicinal purposes. Numerous plant materials have been employed in folk medicine in attempts to control diseases. In many countries around the world the use of medicinal plants still contributes significantly in primary health care. Although there is currently little scientific evidence regarding the efficacy of such treatments, traditional medicine is still widely practiced by people living all over the world. The present study was designed to evaluate the antifungal activity of ethanolic extract of various plant species obtained from various regions and were assayed for in-vitro antifungal activity against human dermatophytes viz: Microsporum gypseum and Trichophyton mentragrophytes. The solvent extract of the plant material was made through Soxehlet Apparatus and was run up to 48 hrs and was tested in two opposite concentrations. Results obtained reveal that the 1:5 concentration of plant material to that of nutrient Broth medium was more effective against dermatophytes as compared to 2:5 ratio. The maximum inhibition was shown by Lindenbergia indica (46.51 %) against Microsporum gypseum in the ratio 1:5, whereas against Trichophyton mentragrophytes was shown by Achyranthus aspera (63.15 %) at the same concentration. However maximum inhibition in the ratio 2:5 against Microsporum gypseum and Trichophyton mentragrophytes was shown by Parthenium hysterophorus (37.20 %) and Lindenbergia indica (52.63 %) respectively.
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Author(s): Javid Iqbal Pandith