alexa Abstract | Phytochemical Analysis and Hydroxyl Radical Scavenging Potential of Murraya exotica L.

Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


The crude extract/fractions of the leaves of Murraya exotica L. have been tested for the qualitative phytochemical analysis, quantitative estimation of total phenolic content and total flavonoid content, hydroxyl radical scavenging activity employing site-specific and non site-specific deoxyribose degradation assay and plasmid nicking assay. The study showed that flavonoids, phenols and tannins were present, but steroids, anthocyanins, proteins, carbohydrates and phlobatanins were absent in the crude extract and its different fractions. It also exhibited the presence of gallic acid, catechin, chlorogenic acid, epicatechin, caffeic acid, umbelliferone, coumaric acid, rutin, tert-Butyl hydroquinone, quercetin and kaempferol in all the fractions viz.; hexane fraction (HF), chloroform fraction (CF), ethyl acetate fraction (EAF), n-Butanol fraction (BF) and water fraction (WF) whereas ellagic acid was detected only in CF. The gallic acid was absent in CF. The investigation involving quantitative estimation of total phenolics showed the highest average of total phenolic content (226.34 μg GAE/mg) in EAF and the highest average of total flavonoids content (304 μg RE/mg) at 1000 μg/ml concentration in CF. HF showed the lowest IC50 value of 1.63 μg/ml in site-specific deoxyribose degradation assay whereas WF showed the lowest IC50 value of 0.00006 μg/ml in non site-specificdeoxyribose degradation assay. In plasmid nicking assay, the crude extract and its fractions viz. HF, CF, EAF, BF and WF exhibited hydroxyl radical scavenging activity in a dose dependent manner, with maximum activity at 1000 μg/ml, whereas EAF at 200 μg/ml exhibited the least activity.

To read the full article Peer-reviewed Article PDF image

Author(s): Saloni Sharma, Saroj Arora

Recommended Journals

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version