alexa Abstract | Prescription Pattern of Anti Hypertensive Drugs used in Hypertensive Patients with Associated Type2 Diabetes Mellitus in A Tertiary Care Hospital


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Research Article Open Access

Abstract

The study aims at the prescription pattern of Antihypertensive agents used in hypertensive patients who have associated Type 2 diabetes mellitus. The objective is to find whether the prescription pattern is in accordance with the Joint National Committee (JNC7) recommended Antihypertensive agents used in the treatment of hypertension with Type 2 diabetes mellitus. This is a prospective study conducted to establish the Antihypertensive drug prescription pattern in hypertensive patients with associated Type 2 Diabetes mellitus who were attending as outpatient in general medicine department at Sri Muthukumaran Medical College & Research Institute over a period of 3 months. The study revealed most of the hypertensive patients with Type 2 diabetes mellitus received combination therapy (75.2%). Commonly prescribed combination therapy was Angiotensin Converting Enzymes inhibitors with Thiazide Diuretics (34.3%), Angiotensin Receptor Blockers with Thiazide Diuretic (26.5%), Angiotensin Converting Enzymes inhibitorswith Calcium channel blockers (23.4%) and Angiotensin Receptor Blockers with Beta Blockers (9.3%), Angiotensin Converting Enzymes inhibitors with Thiazide diuretics and Beta Blockers (6.2%). The hypertensive patients with Type2 diabetes mellitus receiving monotherapy (24.7%) are comparatively lesser. Among the monotherapy category, Angiotensin Converting Enzyme Inhibitors (52.30%) are commonly prescribed class followed by Angiotensin Receptor Blockers (23.80%), Cardioselective Betablockers (9.50%), Calcium Channel Blockers(9.50%)and Diuretics (4.70%). The combination therapy is the most prescribed pattern than monotherapy. The prescription pattern was found to be in concordance with the Joint National Committee (JNC7) recommended treatment of hypertension with Type 2 Diabetes mellitus

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Author(s): T. JANAGAN, R. KAVITHA, S. A. SRIDEVI, V. VEERENDRA

Keywords

Angiotensin converting enzyme inhibitors, angiotensin receptor blockers, antihypertensive agents, joint national committee (JNC7), type 2 diabetes mellitus, Diabetes Research and Clinical Practice,Diabetes Research and Clinical Practice

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