alexa Abstract | Trypsin: A Novel Scavenger of Superoxide Anion
e-ISSN:2320-1215 p-ISSN: 2322-0112

Research & Reviews in Pharmacy and Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

Trypsin is a serine protease found in the digestive system of many vertebrates, where it hydrolyses proteins. The superoxide scavenging activity of trypsin was accidentally found. Results showed that trypsin could scavenge superoxide in both intracorporal and extracorporal systems. The value of km of superoxide scavenging presented by the trypsin was 0.0618 mm The rate of superoxide scavenging increased up to 0.103 μM/μg trypsin/min with the increasing of hydrogen peroxide production rate to a maximum of 0.00122 μM/μg trypsin/min. Trypsin has an optimal operating pH of within 7.5-8.5. The scavenging activity of trypsin was accelerated by copper and impeded by chelators of metals. These indubitable results suggested that trypsin is a novel scavenger of superoxide. The rate of superoxide scavenging and hydrogen peroxide production were impacted by the concentration of trypsin or riboflavin, pH or ions. Trypsin might be a potential drug for anti-oxidant stress in human

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Xin Li, Xinyue Pang, Zichen Tang, Jinle Xiang, Yunhong Liu and Jiaju Qiao

Keywords

Copper, Electron spin resonance, Scavenging activities, Superoxide, Trypsin, Copper, Electron spin resonance, Scavenging activities, Superoxide, Trypsin

Share This Page

Additional Info

Loading
Loading Please wait..
 
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsonline.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsonline.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsonline.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsonline.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsonline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsonline.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsonline.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsonline.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords