Smallpox is spread through inhalation of variola virions (virus particles) via saliva during face-to-face contact, from pus and scabs encountered on bed sheets or other contact vectors Coughing releases large amounts from mucosal lesions in the nose, throat and mouth sphere,. The general symptoms of acquired smallpox begin after an incubation period of 7â17 days The initial symptoms of disease are indistinguishable from many other virus infections with a fever that can spike upwards of 39Â°C and may include myalgia, headache, vomiting, and prostration. This phase may continue for 3-4 days before the appearance of a centrifugally distributed, systemic rash. The rash progresses from a macular to papular stage, after which vesicles evolve on day 4 and pustules on day 7 post fever onset. (Smallpox: New Perspectives Regarding Risk Assessment & Management- Jan-Cedric Hansen)
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Last date updated on June, 2014