Stem cell therapy is a medical treatment that introduces new pluripotent or multipotent stem cells into damaged tissue for curing disease or injury. It has been applied for treating numerous diseases, such as immune disorder, diabetes, neurodegenerative and heart diseases. The first clinical case of stem cell therapy was conducted in late 1950s, which the bone marrow derived haematopoietic stem cells were used for treating the haematological disorders. However, the first success comes out until late 1960s. Currently, the stem cells used in clinics are mostly derived from the somatic one (tissue-specific stem cells), while only few derivate from embryonic stem cells are used in clinical trials. Among them, the intensive use of HSCs gives the best definition in blood-related disorders or in restoration of bone marrow after chemotherapy or radiotherapy. Besides, other somatic stem cells, such as mesenchymal, neural, adipose, and endothelial stem cells have also been reported in treating different diseases. In this article, one case for immunological application with HSCs is discussed, in which the advantage or disadvantage by taking such therapy are mentioned for patients who are interested in stem cell therapy.
Stem Cell Therapy: Are we Ready to use it?- Jia-Ming Chang
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Last date updated on April, 2024