âThe identification of steroid receptors (including AR) in the mid- 1980s led to the definition of a family of ligand-mediated transcription factors that occupy specific chromatic locus for gene regulation. The next chapter in advancements is the identification of cofactors participating chromatin remodeling, including histone writers, erasers, and readers that have continuously been researched up to now. Besides the well-established AR activity in mediating transcriptional activation, recent studies further revealed novel functions of AR in transcriptional repression, genomic translocation, and mTOR activation. Abnormal AR activity is associated with various pathogeneses such as male infertility, androgen-insensitivity syndrome (AIS), polycystic ovarian syndrome (PCOS), spinal and bulbar muscular atrophy (SBMA), rheumatoid arthritis, hirsutism, baldness, acne, breast cancer, and prostate cancer.
Journal of Steroids & Hormonal Science is an official journal of OMICS group international that publishes the articles related to androgen receptor phosphorylation. The peer review followed by Journal of Steroids & Hormonal Science is single blind peer review process. This sort of review process will enable the authors to make the required manipulations and improve the quality of their work as per the experts opinion. The journal is publishing all the articles related to androgen receptors under a special issue entitled Androgen Receptors.
Last date updated on July, 2014