In aging males, low testosterone levels are predictive of future development of mobility limitations and frailty. Androgen replacement therapy (ART) in elderly male subjects has been considered as a restorative/protective treatment modality against various disorders associated with aging. ART is currently only indicated by the FDA for males that have been diagnosed with hypogonadism. The Endocrine Societys clinical practical guideline for ART in adult men with testosterone deficiency has defined hypogonadism in males as a clinical syndrome that results from failure of the testis to produce physiological levels of testosterone and a normal number of spermatozoa due to a disruption of one or more levels of the hypothalamic-pituitary-gonadal (HPG) axis. Primary hypogonadism is characterized by high luteinizing hormone and follicle stimulating hormone levels in response to diminished HPG feedback, while secondary hypogonadism is characterized by low testosterone levels associated with low or normal luteinizing hormone or follicle stimulating hormone levels.
Journal of Steroids & Hormonal Science a journal of OMICS group international that publishes the articles related to androgen replacement therapy. The peer review followed by Journal of Steroids & Hormonal Science is single blind peer review process. This sort of review process will enable the authors to make the required manipulations and improve the quality of their work as per the experts opinion. The unofficial impact factor of Journal of Steroids & Hormonal Science is 3.125.
Last date updated on June, 2014