Central hypothyroidism (CH) refers to hypothyroidism that is not caused by anatomical or functional defects of the thyroid gland per se (primary hypothyroidism) but by inefficient synthesis of TSH (secondary hypothyroidism). Central hypothyroidism might be congenital (CH-C) or acquired. The TSH values in individuals with central hypothyroidism would be expected to be subnormal. Although that is usually the case, normal or mildly elevated TSH values can also be detected in certain cases, leading to an erroneous diagnosis of primary hypothyroidism. This phenomenon has been attributed to an aberrant TSH molecule, which is measurable by applied methodology but is biologically inactive. Regardless of the mechanism involved one should be aware of this phenomenon in order to avoid misinterpretation and diagnose primary instead of secondary (central) hypothyroidism.
The Journal of Steroids & Hormonal Science publishes the papers related to Central hypothyroidism. The journal is open access where the content is available freely for the readers and the papers which will be published are assessed by experts for the quality. The journal is having professors and associate professors as its editorial board members.
Last date updated on September, 2020