âErythropoietin (Epo) is a glycoprotein hormone (40% carbohydrate) with a molecular weight of 32-39 KDa that controls erythropoiesis, in the bone marrow. It is produced mainly by the peri-tubular capillary endothelial cells in the kidney but also in the liver.
Synthetic or pharmaceutical erythropoietins, Epoetins (Epos) or recombinant human erythropoietins (rhEpos), consist of epoetin alfa, beta, theta, and zeta. These erythropoiesis-stimulating agents (ESAs) are commercially available and are used to treat symptomatic anaemia associated with erythropoietin deficiency in chronic renal failure, to increase the yield of autologous blood in normal individuals and to shorten the period of symptomatic anaemia in patients receiving cytotoxic chemotherapy. Journal of Steroids & Hormonal Science is an Erythropoietin related journal that publishes original articles, literature of review, case reports, letter to editors related to erythropoietin.
Last date updated on June, 2014