Melatonin levels decline with age, and the nocturnal peak is almost lost which contributes to the homeostatic sleep drive decreasing with age. The circadian clock advances or shifts earlier with ageing, and may play a role in sleep problems in the aged. The need for day-time naps is often related to poor night-time sleep, but may be related to the primarily disturbed circadian rhythms in the elderly. Because of relative safety and its role in the pathogenesis, melatonin should be a consideration when treating these patients. Various age-related physiological changes may be modulated by the decrease in melatonin, and some authors have suggested supplemental melatonin to be beneficial in general age-related deterioration.
Journal of Steroids & Hormonal Science is an official journal of OMICS group international that publishes the articles related to melatonin and aging. The peer review followed by Journal of Steroids & Hormonal Science is single blind peer review process. This sort of review process will enable the authors to make the required manipulations and improve the quality of their work as per the experts opinion.
Last date updated on June, 2014