The thyroid gland, or simply the thyroid, in vertebrate anatomy, is one of the largest endocrine glands and consists of two connected lobes. The thyroid gland is found in the neck, below the thyroid cartilage. The thyroid gland controls how quickly the body uses energy, makes proteins, and controls how sensitive the body is to other hormones.Unrecognized thyrotoxicosis can be complicated by thyroid storm which is a serious medical condition associated with a mortality rate of 20-30% , although the most recent data suggest it is around 10%. Mortality rate can be high also in untreated hypothyroidism which progresses to myxedema coma that carries a mortality rate of 20-25%, despite intensive supportive care delivered to patients with such complication.The spectrum of thyroid dysfunction encompasses various grades of hypothyroidism and hyperthyroidism, from subclinical to mild and overt, while thyroid storm and myxedema coma represent the very two extremes. Both of them are rare but life-threatening events and carry a high mortality rate even with best possible treatment. Early diagnosis is of critical importance but it may not be easy to recognise these two extremes of thyroid dysfunction, especially in patients with no previous history of thyroid disorders and are seen in a comatose state.
A journal is a periodical publication intended to further progress of science, usually by reporting new research. Most journals are highly specialized, although some of the oldest journals publish articles, reviews, editorials, short communications, letters, and scientific papers across a wide range of scientific fields. Journals contain articles that peer reviewed, in an attempt to ensure that articles meet the journal's standards of quality, and scientific validity. Each such journal article becomes part of the permanent scientific record.
Last date updated on June, 2014