α-tocopherol

α-tocopherol (α-T) out of the 8 major analogues of vitamin E has been a particular focus because of its strong antioxidant properties. α-T is enriched in the plasma of humans and higher animals 10-100-fold to an average of 23.2 μM. In Vitamin E isomers, α-T is a fat-soluble vitamin, where as it phosphate form, α-tocopherol phosphate (α-TP) is naturally occurring water-soluble form. α-T has strong antioxidant activity, the chromanol OH group in α-TP is phosphorylated so that it has no antioxidant activity. α-TP acts as a detergent forming a barrier which might inhibit the transfer of free radicals from one polyunsaturated fatty acid. α-TP more efficiently modulated atherosclerotic and inflammatory events than α-T by reducing THP-1 cell proliferation and expression of the CD36 scavenger receptor. α-TP and α-T act as lipid mediators modulating signal transduction and gene expression. Michael Eskin NA https://www.omicsonline.org/open-access/vitamin-e-and-the-role-of-watersoluble-tocopheryl-phosphate-vms.1000e123.php?aid=24737 Vitamins & minerals is one of the best indexed journals in the field of nutrition and essential micro nutrients field of science, publishes the ongoing scientific research in the form of original research, review, case reports, editorials with the main focus on the quality of publishing. By the eminent personalities from the editorial and reviewer board, ensuring of the high quality and originality of the published content is achieved. OMICS Group International has been indexing all articles of Vitamins & minerals to enhance visibility and credibility. It has a repertoire of over 700+ peer-reviewed journals of which, quality and originality are insured by 50,000+ editorial board members.

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Last date updated on April, 2024