Î±-tocopherol (Î±-T) out of the 8 major analogues of vitamin E has been a particular focus because of its strong antioxidant properties. Î±-T is enriched in the plasma of humans and higher animals 10-100-fold to an average of 23.2 Î¼M. In Vitamin E isomers, Î±-T is a fat-soluble vitamin, where as it phosphate form, Î±-tocopherol phosphate (Î±-TP) is naturally occurring water-soluble form. Î±-T has strong antioxidant activity, the chromanol OH group in Î±-TP is phosphorylated so that it has no antioxidant activity. Î±-TP acts as a detergent forming a barrier which might inhibit the transfer of free radicals from one polyunsaturated fatty acid. Î±-TP more efficiently modulated atherosclerotic and inflammatory events than Î±-T by reducing THP-1 cell proliferation and expression of the CD36 scavenger receptor. Î±-TP and Î±-T act as lipid mediators modulating signal transduction and gene expression.
Michael Eskin NA
Vitamins & Minerals is the best peer-reviewed journals in related to nutrition scope journals from OMICS International publishing group. Articles published in this peer-reviewed journal have a rapid peer review process and are reviewed by at least two reviewers form the related expertise fields. Two comments like major and minor is followed for quality of the articles and final decision rests on the editor for the respective articles from editorial board of the journal.
Vitamins & Minerals peer review journals covers the broader scopes stressing on the topics of hypervitaminosis, hypovitaminosis D, multivitamins, fat soluble vitamins, water soluble vitamins including but not limited to the above discussed fields.
OMICS Group is one of the best international publishers with 700+ peer-reviewed journals along with eminent scientists in its Editorial Board and expert reviewers to carry rigorous peer-review process. The peer review process is highly appreciated by researchers globally. In addition to peer review open-access publishing, OMICS also provides E-books, Scholar Central and more than 3000+ International Scientific Conferences under its umbrella.
Last date updated on June, 2014