"Transfer-RNA was proposed by Crick as a necessity to ââ¬Åadaptââ¬Â the codon to the encoded amino acid (a codon is three times longer than an amino acid). However, it became apparent that tRNA is approximately 20-times larger than necessary for this role. The ââ¬Åadaptorââ¬Â became a clumsy ââ¬Åbarrierââ¬Â between the nucleic acid and protein worlds. Therefore, radical revision of the function of tRNA was necessary to understand the transfer of spatial information fromnucleic acids to peptides, and to make sense of the size and frequency of tRNA-s.
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Citation: Biro JC (2014) Suggestion to Upgrade the Canonical Concept of Translation. J Proteomics Bioinform 7: 112-120."
Last date updated on September, 2024
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