The incidence of brain cancer has generally been slowly increasing since beginning of the 20th century, and has in several countries stabilized in recent years. Our first hypothesis is that this increase was caused by environmental changes that may reduce the efficiency of the DNA repair system in the brain. For every year during a personâs life a certain amount of brain DNA damage occurs, either ânaturallyâ, or due to external environmental influence. A âlife matrixâ is defined where the partial cancer risks originating from each year of a personâs life are added vertically together. For example, each birth cohort from 1880 to 1980 is attributed with its own life matrix thus making it possible to calculate the age-specific incidence rates over calendar time. It is too early to predict future rates of brain cancer, but these preliminary findings suggest that we should prepare for about a doubled brain cancer incidence rate and possibly as high as 25 times the incidence we have today. Brain and CNS cancer has been increasing in many countries since roughly 1950, possibly due to the introduction of immune disturbing technologies such as electricity.
Last date updated on July, 2014