"Proteins are assumed to contain all necessary information for unambiguous folding (Anfinsenââ¬â¢s principle). However, ab initio structure prediction is often unsuccessful, as the amino acid sequence itself is not sufficient to guide among endless folding possibilities. It seems logical to attempt to find the ââ¬Åmissingââ¬Â information in nucleic acids, specifically in redundant (synonymous) codons and their wobble bases.
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Citation: Biro JC (2014) Suggestion to Upgrade the Canonical Concept of Translation. J Proteomics Bioinform 7: 112-120."
Last date updated on September, 2024
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