MarfanÂ’s syndrome is an autosomal dominant connective tissue disorder. Connective tissue strengthens the body structures. It is characterized by the mutations in gene FBN-1. Glycoprotein fibrillin-1 is encoded by FBN-1. Fibrillin-1 contributes to formation of elastin and the extracellular matrix. Blood vessels are commonly affected by this syndrome as connective tissue is present abundantly in them. Their elasticity gets altered which later results in aneurysm and rupture.
The open access journals are peer reviewed scholarly journals of Journal of Allergy and Therapy. The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open access journals are indexed in SCOPUS, COPERNICUS, CAS, EBSCO and ISI.
Last date updated on June, 2014