MarfanÂ’s syndrome is an autosomal dominant connective tissue disorder. Connective tissue strengthens the body structures. It is characterized by the mutations in gene FBN-1. Glycoprotein fibrillin-1 is encoded by FBN-1. Fibrillin-1 contributes to formation of elastin and the extracellular matrix. Blood vessels are commonly affected by this syndrome as connective tissue is present abundantly in them. Their elasticity gets altered which later results in aneurysm and rupture.
Review articles are the summary of current state of understanding on a particular research topic. They analyze or discuss research previously published by scientist and academicians rather than reporting novel research results.
Review article comes in the form of systematic reviews and literature reviews and are a form of secondary literature. Systematic reviews determine an objective list of criteria, and find all previously published original research papers that meet the criteria. They then compare the results presented in these papers. Literature reviews, by contrast, provide a summary of what the authors believe are the best and most relevant prior publications.
The concept of "review article" is separate from the concept of peer-reviewed literature. It is possible for a review to be peer-reviewed, and it is possible for a review to be non-peer-reviewed.
Last date updated on June, 2014