|Vaccination is the administration of antigenic material vaccine to stimulate an individual's immune system to develop adaptive immunity to a pathogen. Vaccines can prevent morbidity from infection. Vaccination began in the 18th century with the work of Edward Jenner. The effectiveness of vaccination has been widely studied and verified; for example, the influenza vaccine, the HPV vaccine, and the chicken pox vaccine. Vaccination is the most effective method of preventing infectious diseases; widespread immunity due to vaccination is largely responsible for the worldwide eradication of smallpox and the restriction of diseases such as polio, measles, and tetanus from much of the world. The World Health Organization (WHO) reports licensed vaccines are currently available to prevent, or contribute to the prevention and control of, 25 vaccine-preventable infections. The Toxoids are produced for immunization against toxin-based diseases, such as the modification of tetanospasmin toxin of tetanus to remove its toxic effect but retain its immunogenic effect. Vaccination includes various ways of administering immunogens : inactivated vaccine; attenuated vaccine; Virus-like particle; subunit vaccine. The number of other vaccine strategies is under experimental investigation. These include DNA vaccination and recombinant viral vectors. OMICS Group International through its Open Access Initiative is committed to make genuine and reliable contributions to the scientific community.
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