Psoriatic arthritis is a chronic, progressive, inflammatory arthropathy associated with psoriasis. PsA is progressive, erosive, and destructive, resulting in marked impairment of the activities of daily living and poor quality of life. Patients with PsA are usually affected with psoriasis before signs of joint disease have developed. Although not life-threatening, psoriasis substantially affects health-related quality of life and has negative psychological and social implications. A comparative study reported reduction in physical functioning and mental functioning comparable with these seen in cancer. Traditional disease modifying anti-rheumatic drugs (DMARDs) have shown inconsistent and unsatisfactory results. Treatment with biological agents has shown different results. Despite the evident efficacy of biologic agents for psoriatic arthritis and psoriasis, there is an increase in psoriasis following biologic agents therapies. Psoriasis has no permanent cure and represents a lifelong burden for affected patients.
Successful Treatment of Severe Psoriatic Arthritis and Psoriasis with Double Filtration Plasmapheresis: Xiaoxia Yu, Lei Zhang and Peng Zhang
Last date updated on July, 2014