|It is a clinical condition in which heart is not able to pump adequately to maintain blood flow to meet the requirement of body. The foremost cause of heart failure is coronary artery diseases, myocardial infarction, high blood pressure and atrial fibrillation etc. common sign and symptoms are increased rate of breathing, initially rales can be hear from lung bases or pulmonary edema, and wheezing etc.Peer review refers to the work done during the screening of submittedÂ manuscriptsÂ and funding applications. This process encourages authors to meet the acceptedÂ standardsÂ of their discipline and reduces the dissemination of irrelevant findings, unwarranted claims, unacceptable interpretations, and personal views. Publications that have not undergone peer review are likely to be regarded with suspicion by academic scholars and professionals.